Proteomics (Olink)

Summary

Number of traits: 308
Training cohort: INTERVAL
Training sample size: 4,822

External validation cohort: NSPHS and ORCADES
Number of traits externally validated: 302 and 301
External cohort sample sizes: 872 and 1,052
Evaluation Metric: Spearman correlation coefficient, r squared (r2)

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All genetic scores are provided under a CC-BY license.

Validation performance of genetic scores

drawing

(a1): Spearman correlation performance comparison between internal and external validation (NSPHS);
(a2): Spearman correlation performance comparison between internal and external validation (ORCADES);
(b): The number of traits whose genetic scores are in different performance ranges in terms of explained variance (R2) between internal and external validation (NSPHS).

Explore traits and their genetic scores

UniProt ID Gene Protein #SNP r2 EXT1.r2 EXT2.r2
P31994 FCGR2B Low affinity immunoglobulin gamma Fc region receptor II-b 363 0.61 0.51 0.46
O00175 CCL24 C-C motif chemokine 24 222 0.56 0.45 0.32
P08887 IL6R Interleukin-6 receptor subunit alpha 168 0.54 0.72 0.26
Q8NFP4 MDGA1 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 201 0.52 0.56 0.45
P78324 SIRPA Tyrosine-protein phosphatase non-receptor type substrate 1 110 0.52 0.7 0.27
Q96F46 IL17RA Interleukin-17 receptor A 92 0.49 0.75 0.28
Q8TDQ1 CD300LF CMRF35-like molecule 1 88 0.47 0.61 0.47
Q13231 CHIT1 Chitotriosidase-1 99 0.45 0.43 0.31
Q8IW75 SERPINA12 Serpin A12 97 0.41 0.3 0.32
O15444 CCL25 C-C motif chemokine 25 170 0.4 0.33 0.34
P13598 ICAM2 Intercellular adhesion molecule 2 223 0.36 0.45 0.19
O14798 TNFRSF10C Tumor necrosis factor receptor superfamily member 10C 83 0.36 0.45 0.2
Q16663 CCL15 C-C motif chemokine 15 76 0.36 0.31 0.19
P80075 CCL8 C-C motif chemokine 8 94 0.36 0.33 0.31
P35247 SFTPD Pulmonary surfactant-associated protein D 416 0.34 0.31 0.21
O15467 CCL16 C-C motif chemokine 16 55 0.34 0.49 0.21
Q01638 IL1RL1 Interleukin-1 receptor-like 1 184 0.34 0.28 0.14
Q13478 IL18R1 Interleukin-18 receptor 1 182 0.33 0.47 0.2
Q9Y336 SIGLEC9 Sialic acid-binding Ig-like lectin 9 137 0.33 0.4 0.37
Q6ISS4 LAIR2 Leukocyte-associated immunoglobulin-like receptor 2 73 0.33 0.29 0.21
Q8TD46 CD200R1 Cell surface glycoprotein CD200 receptor 1 134 0.32 0.35 0.28
P53634 CTSC Dipeptidyl peptidase 1 174 0.28 0.25 0.17
Q8WWJ7 CD6 T cell surface glycoprotein CD6 isoform e 89 0.28 0.19 0.21
P16581 SELE E-selectin 121 0.27 0.3 0.17
P78333 GPC5 Glypican-5 149 0.27 0.47 0.3
Q8IYS5 OSCAR Osteoclast-associated immunoglobulin-like receptor 96 0.27 0.25 0.19
P35475 IDUA Alpha-L-iduronidase 236 0.26 0.2 0.19
P15151 PVR Poliovirus receptor 54 0.26 0.33 0.25
Q8NEV9;Q14213 IL27A;IL27B Interleukin-27 subunit alpha;beta 71 0.26
O75077 ADAM23 Disintegrin and metalloproteinase domain-containing protein 23 155 0.26 0.36 0.23
Q9BQ51 PDCD1LG2 Programmed cell death 1 ligand 2 139 0.24 0.25 0.24
Q9H3S3 TMPRSS5 Transmembrane protease serine 5 144 0.24 0.32 0.21
Q96D42 HAVCR1 Hepatitis A virus cellular receptor 1 136 0.24 0.15 0.17
Q08708 CD300C CMRF35-like molecule 6 77 0.23 0.52 0.25
P09874 PARP1 Poly 111 0.22 0.0 0.0
P29460 IL12B Interleukin-12 subunit beta 95 0.22 0.27 0.15
P28325 CST5 Cystatin-D 124 0.22 0.22 0.28
P01374 LTA Lymphotoxin-alpha 519 0.22 0.09 0.12
Q96LA5 FCRL2 Fc receptor-like protein 2 155 0.22 0.26 0.2
P04080 CSTB Cystatin-B 137 0.22 0.18 0.02
Q9NR71 ASAH2 Neutral ceramidase 141 0.22 0.2 0.16
P00813 ADA Adenosine deaminase 81 0.22 0.05 0.1
P30533 LRPAP1 Alpha-2-macroglobulin receptor-associated protein 533 0.22 0.07 0.31
Q92765 FRZB Secreted frizzled-related protein 3 100 0.21 0.1 0.16
P35218 CA5A Carbonic anhydrase 5A mitochondrial 63 0.21 0.26 0.22
P36222 CHI3L1 Chitinase-3-like protein 1 37 0.2 0.32 0.14
Q02083 NAAA N-acylethanolamine-hydrolyzing acid amidase 133 0.2 0.22 0.16
P25774 CTSS Cathepsin S 155 0.2 0.21 0.07
P29460;P29459 IL12A;IL12B Interleukin-12 subunit alpha;beta 76 0.19
P01589 IL2RA Interleukin-2 receptor subunit alpha 96 0.19 0.26 0.1
Q8NF90 FGF5 Fibroblast growth factor 5 51 0.19 0.07 0.08
P28799 GRN Progranulin 79 0.19 0.33 0.08
Q9BQR3 PRSS27 Serine protease 27 107 0.19 0.16 0.2
O15232 MATN3 Matrilin-3 102 0.19 0.1 0.12
Q01344 IL5RA Interleukin-5 receptor subunit alpha 63 0.18 0.2 0.13
P33151 CDH5 Cadherin-5 119 0.18 0.29 0.12
Q02763 TEK Angiopoietin-1 receptor 110 0.18 0.29 0.14
O00220 TNFRSF10A Tumor necrosis factor receptor superfamily member 10A 43 0.18 0.33 0.16
O94779 CNTN5 Contactin-5 125 0.18 0.22 0.23
Q76LX8 ADAMTS13 A disintegrin and metalloproteinase with thrombospondin motifs 13 103 0.18 0.03 0.04
Q99895 CTRC Chymotrypsin-C 77 0.18 0.14 0.15
P47992 XCL1 Lymphotactin 68 0.17 0.24 0.14
Q13261 IL15RA Interleukin-15 receptor subunit alpha 57 0.17 0.15 0.12
Q9HB29 IL1RL2 Interleukin-1 receptor-like 2 128 0.17 0.2 0.13
Q8IUN9 CLEC10A C-type lectin domain family 10 member A 70 0.17 0.22 0.12
P08254 MMP3 Stromelysin-1 100 0.17 0.09 0.06
P17931 LGALS3 Galectin-3 154 0.16 0.1 0.05
P09238 MMP10 Stromelysin-2 75 0.16 0.07 0.09
P55773 CCL23 C-C motif chemokine 23 40 0.16 0.17 0.1
O00182 LGALS9 Galectin-9 87 0.16 0.2 0.12
P26022 PTX3 Pentraxin-related protein PTX3 58 0.16 0.01 0.04
Q9Y6Q6 TNFRSF11A Tumor necrosis factor receptor superfamily member 11A 120 0.15 0.2 0.1
P80511 S100A12 Protein S100-A12 94 0.15 0.0 0.01
P27352 CBLIF Cobalamin binding intrinsic factor 127 0.15 0.12 0.11
Q14005 IL16 Pro-interleukin-16 68 0.15 0.06 0.19
Q9P0K1 ADAM22 Disintegrin and metalloproteinase domain-containing protein 22 72 0.15 0.4 0.14
Q14790 CASP8 Caspase-8 87 0.15 0.01 0.0
Q9BZZ2 SIGLEC1 Sialoadhesin 27 0.14 0.09 0.14
P17405 SMPD1 Sphingomyelin phosphodiesterase 67 0.14 0.16 0.13
P35442 THBS2 Thrombospondin-2 62 0.14 0.09 0.08
Q14116 IL18 Interleukin-18 91 0.14 0.0 0.0
Q9NQ25 SLAMF7 SLAM family member 7 57 0.14 0.13 0.12
P03956 MMP1 Interstitial collagenase 97 0.14 0.16 0.1
O00214 LGALS8 Galectin-8 85 0.14 0.41 0.16
P18510 IL1RN Interleukin-1 receptor antagonist protein 95 0.14 0.0 0.0
P39900 MMP12 Macrophage metalloelastase 79 0.14 0.16 0.17
Q14242 SELPLG P-selectin glycoprotein ligand 1 22 0.14 0.22 0.22
Q13867 BLMH Bleomycin hydrolase 91 0.14 0.17 0.13
P24158 PRTN3 Myeloblastin 35 0.14 0.2 0.05
P13236 CCL4 C-C motif chemokine 4 123 0.14 0.27 0.12
Q9BZM5 ULBP2 UL16-binding protein 2 58 0.13 0.33 0.1
P06858 LPL Lipoprotein lipase 40 0.13 0.03 0.12
Q08334 IL10RB Interleukin-10 receptor subunit beta 40 0.13 0.21 0.12
Q2TAL6 VWC2 Brorin 31 0.13 0.16 0.16
Q9UK05 GDF2 Growth/differentiation factor 2 82 0.13 0.03 0.13
P08473 MME Neprilysin 87 0.13 0.25 0.1
O43155 FLRT2 Leucine-rich repeat transmembrane protein FLRT2 61 0.13 0.3 0.11
P50591 TNFSF10 Tumor necrosis factor ligand superfamily member 10 42 0.13 0.09 0.08
P80370 DLK1 Protein delta homolog 1 85 0.12 0.13 0.08
P15692 VEGFA Vascular endothelial growth factor A 32 0.12 0.2 0.03
P10646 TFPI Tissue factor pathway inhibitor 85 0.12 0.16 0.04
Q2VWP7 PRTG Protogenin 57 0.12 0.23 0.11
P27930 IL1R2 Interleukin-1 receptor type 2 85 0.12 0.26 0.03
P15144 ANPEP Aminopeptidase N 44 0.11 0.19 0.03
Q9H3U7 SMOC2 SPARC-related modular calcium-binding protein 2 79 0.11 0.14 0.08
P55285 CDH6 Cadherin-6 66 0.11 0.17 0.08
Q8NBI3 DRAXIN Draxin 35 0.11 0.13 0.07
Q5T2D2 TREML2 Trem-like transcript 2 protein 48 0.11 0.2 0.07
P80162 CXCL6 C-X-C motif chemokine 6 23 0.1 0.3 0.16
P48052 CPA2 Carboxypeptidase A2 37 0.1 0.06 0.11
Q92583 CCL17 C-C motif chemokine 17 50 0.1 0.16 0.1
Q15166 PON3 Serum paraoxonase/lactonase 3 46 0.1 0.19 0.08
Q86VB7 CD163 Scavenger receptor cysteine-rich type 1 protein M130 36 0.1 0.06 0.03
P13686 ACP5 Tartrate-resistant acid phosphatase type 5 48 0.1 0.11 0.03
P02786 TFRC Transferrin receptor protein 1 142 0.1 0.06 0.03
P56470 LGALS4 Galectin-4 45 0.1 0.08 0.08
P15311 EZR Ezrin 71 0.1 0.0 0.0
O43557 TNFSF14 Tumor necrosis factor ligand superfamily member 14 56 0.1 0.08 0.02
P21757 MSR1 Macrophage scavenger receptor types I and II 32 0.1 0.04 0.09
P10147 CCL3 C-C motif chemokine 3 33 0.09 0.06 0.05
O14763 TNFRSF10B Tumor necrosis factor receptor superfamily member 10B 21 0.09 0.11 0.08
P07339 CTSD Cathepsin D 71 0.09 0.13 0.05
Q96GP6 SCARF2 Scavenger receptor class F member 2 48 0.09 0.21 0.08
Q9UBR2 CTSZ Cathepsin Z 50 0.09 0.16 0.06
P09237 MMP7 Matrilysin 19 0.09 0.04 0.04
P22004 BMP6 Bone morphogenetic protein 6 44 0.08 0.05 0.13
P01730 CD4 T-cell surface glycoprotein CD4 113 0.08 0.08 0.02
Q92752 TNR Tenascin-R 23 0.08 0.15 0.1
Q99988 GDF15 Growth/differentiation factor 15 17 0.08 0.08 0.02
O95727 CRTAM Cytotoxic and regulatory T-cell molecule 22 0.08 0.14 0.11
P28907 CD38 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 34 0.08 0.06 0.05
Q99727 TIMP4 Metalloproteinase inhibitor 4 55 0.08 0.1 0.03
P25942 CD40 Tumor necrosis factor receptor superfamily member 5 50 0.08 0.25 0.11
Q13043 STK4 Serine/threonine-protein kinase 4 60 0.08 0.0 0.0
Q9HD89 RETN Resistin 14 0.08 0.17 0.04
Q13219 PAPPA Pappalysin-1 41 0.08 0.0 0.06
P05164 MPO Myeloperoxidase 33 0.08 0.12 0.04
Q9H5V8 CDCP1 CUB domain-containing protein 1 29 0.07 0.08 0.06
Q9BS40 LXN Latexin 21 0.07 0.0 0.02
P50225 SULT1A1 Sulfotransferase 1A1 48 0.07 0.0 0.0
Q6UX15 LAYN Layilin 35 0.07 0.2 0.06
P51888 PRELP Prolargin 26 0.07 0.04 0.09
Q9BZW8 CD244 Natural killer cell receptor 2B4 21 0.07 0.05 0.04
Q13541 EIF4EBP1 Eukaryotic translation initiation factor 4E-binding protein 1 56 0.07 0.0 0.0
P36941 LTBR Tumor necrosis factor receptor superfamily member 3 20 0.07 0.19 0.03
Q07654 TFF3 Trefoil factor 3 352 0.07 0.02 0.01
P13726 F3 Tissue factor 64 0.07 0.1 0.09
Q99616 CCL13 C-C motif chemokine 13 30 0.07 0.24 0.04
Q96PL1 SCGB3A2 Secretoglobin family 3A member 2 21 0.06 0.01 0.03
Q12866 MERTK Tyrosine-protein kinase Mer 29 0.06 0.07 0.04
Q9Y275 TNFSF13B Tumor necrosis factor ligand superfamily member 13B 30 0.06 0.02 0.03
P37023 ACVRL1 Serine/threonine-protein kinase receptor R3 23 0.06 0.09 0.07
O14788 TNFSF11 Tumor necrosis factor ligand superfamily member 11 25 0.06 0.01 0.04
Q96B86 RGMA Repulsive guidance molecule A 38 0.06 0.13 0.03
Q96IQ7 VSIG2 V-set and immunoglobulin domain-containing protein 2 38 0.06 0.11 0.04
O43157 PLXNB1 Plexin-B1 25 0.06 0.02 0.07
P07204 THBD Thrombomodulin 46 0.06 0.06 0.04
P02778 CXCL10 C-X-C motif chemokine 10 3 0.06 0.27 0.0
O95185 UNC5C Netrin receptor UNC5C 54 0.06 0.07 0.03
Q8N126 CADM3 Cell adhesion molecule 3 21 0.06 0.07 0.02
Q8TAD2 IL17D Interleukin-17D 48 0.06 0.06 0.05
P01135 TGFA Protransforming growth factor alpha 48 0.06 0.0 0.0
P04216 THY1 Thy-1 membrane glycoprotein 20 0.06 0.14 0.06
Q9HAN9 NMNAT1 Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 38 0.06 0.01 0.03
P21583 KITLG Kit ligand 26 0.06 0.04 0.03
P19957 PI3 Elafin 34 0.05 0.05 0.01
P51161 FABP6 Gastrotropin 53 0.05 0.0 0.05
P01130 LDLR Low-density lipoprotein receptor 18 0.05 0.02 0.0
Q12860 CNTN1 Contactin-1 40 0.05 0.11 0.03
P16109 SELP P-selectin 12 0.05 0.12 0.03
Q6ZMJ2 SCARA5 Scavenger receptor class A member 5 22 0.05 0.06 0.04
Q92823 NRCAM Neuronal cell adhesion molecule 33 0.05 0.03 0.03
P16422 EPCAM Epithelial cell adhesion molecule 34 0.05 0.07 0.04
Q8NBP7 PCSK9 Proprotein convertase subtilisin/kexin type 9 31 0.05 0.08 0.01
Q99731 CCL19 C-C motif chemokine 19 74 0.05 0.05 0.03
Q08345 DDR1 Epithelial discoidin domain-containing receptor 1 33 0.05 0.17 0.02
Q13291 SLAMF1 Signaling lymphocytic activation molecule 24 0.05 0.01 0.02
Q96NZ8 WFIKKN1 WAP Kazal immunoglobulin Kunitz and NTR domain-containing protein 1 17 0.05 0.1 0.04
P20160 AZU1 Azurocidin 10 0.05 0.02 0.03
P01833 PIGR Polymeric immunoglobulin receptor 30 0.05 0.0 0.03
Q16270 IGFBP7 Insulin-like growth factor-binding protein 7 50 0.05 0.04 0.01
P31997 CEACAM8 Carcinoembryonic antigen-related cell adhesion molecule 8 13 0.04 0.03 0.04
P42830 CXCL5 C-X-C motif chemokine 5 17 0.04 0.19 0.11
P12544 GZMA Granzyme A 313 0.04 0.04 0.02
O14836 TNFRSF13B Tumor necrosis factor receptor superfamily member 13B 10 0.04 0.02 0.02
Q04760 GLO1 Lactoylglutathione lyase 33 0.04 0.18 0.08
P16234 PDGFRA Platelet-derived growth factor receptor alpha 12 0.04 0.05 0.03
Q16719 KYNU Kynureninase 23 0.04 0.02 0.02
P56159 GFRA1 GDNF family receptor alpha-1 23 0.04 0.12 0.04
P13500 CCL2 C-C motif chemokine 2 9 0.04 0.05 0.0
P16860 NPPB Natriuretic peptides B 38 0.04 0.02 0.02
Q9HCB6 SPON1 Spondin-1 23 0.04 0.05 0.02
P14778 IL1R1 Interleukin-1 receptor type 1 34 0.04 0.06 0.01
P42702 LIFR Leukemia inhibitory factor receptor 32 0.04 0.02 0.04
Q9UEW3 MARCO Macrophage receptor MARCO 17 0.04 0.01 0.04
Q9UBT3 DKK4 Dickkopf-related protein 4 18 0.04 0.0 0.05
P78423 CX3CL1 Fractalkine 34 0.04 0.04 0.02
P04792 HSPB1 Heat shock protein beta-1 20 0.04 0.18 0.03
P51671 CCL11 Eotaxin 11 0.04 0.06 0.0
P49771 FLT3LG Fms-related tyrosine kinase 3 ligand 5 0.04 0.06 0.08
P06127 CD5 T-cell surface glycoprotein CD5 15 0.04 0.03 0.02
Q8NFT8 DNER Delta and Notch-like epidermal growth factor-related receptor 20 0.04 0.03 0.03
P39905 GDNF Glial cell line-derived neurotrophic factor 9 0.04 0.0 0.06
P00749 PLAU Urokinase-type plasminogen activator 11 0.04 0.06 0.04
Q14108 SCARB2 Lysosome membrane protein 2 37 0.04 0.07 0.03
P16284 PECAM1 Platelet endothelial cell adhesion molecule 28 0.03 0.15 0.04
P10451 SPP1 Osteopontin 40 0.03 0.01 0.01
O43915 VEGFD Vascular endothelial growth factor D 19 0.03 0.01 0.02
O00300 TNFRSF11B Tumor necrosis factor receptor superfamily member 11B 20 0.03 0.03 0.02
P24394 IL4R Interleukin-4 receptor subunit alpha 17 0.03 0.06 0.04
Q99969 RARRES2 Retinoic acid receptor responder protein 2 14 0.03 0.02 0.0
Q9UIB8 CD84 SLAM family member 5 8 0.03 0.07 0.02
Q8IXJ6 SIRT2 NAD-dependent protein deacetylase sirtuin-2 26 0.03 0.0 0.0
P22301 IL10 Interleukin-10 9 0.03 0.0 0.0
P98160 HSPG2 Basement membrane-specific heparan sulfate proteoglycan core protein 16 0.03 0.07 0.02
P09601 HMOX1 Heme oxygenase 1 11 0.03 0.03 0.03
O75594 PGLYRP1 Peptidoglycan recognition protein 1 11 0.03 0.06 0.01
P12104 FABP2 Fatty acid-binding protein intestinal 43 0.03 0.04 0.03
P30530 AXL Tyrosine-protein kinase receptor UFO 16 0.03 0.02 0.01
Q9H2A7 CXCL16 C-X-C motif chemokine 16 21 0.03 0.05 0.01
Q99523 SORT1 Sortilin 15 0.03 0.07 0.02
Q9NQ76 MEPE Matrix extracellular phosphoglycoprotein 8 0.03 0.01 0.0
P25445 FAS Tumor necrosis factor receptor superfamily member 6 13 0.03 0.06 0.01
P05107 ITGB2 Integrin beta-2 9 0.03 0.0 0.01
P41217 CD200 OX-2 membrane glycoprotein 13 0.03 0.11 0.03
P14384 CPM Carboxypeptidase M 9 0.03 0.02 0.0
P08253 MMP2 72 kDa type IV collagenase 25 0.03 0.02 0.0
Q9BWV1 BOC Brother of CDO 7 0.03 0.04 0.03
P05231 IL6 Interleukin-6 3 0.03 0.03 0.02
P15086 CPB1 Carboxypeptidase B 19 0.03 0.03 0.03
O43508 TNFSF12 Tumor necrosis factor ligand superfamily member 12 46 0.03 0.03 0.0
P09341 CXCL1 Growth-regulated alpha protein 13 0.03 0.11 0.12
Q07325 CXCL9 C-X-C motif chemokine 9 10 0.03 0.03 0.01
Q9BUD6 SPON2 Spondin-2 21 0.03 0.01 0.03
P01137 TGFB1 Transforming growth factor beta-1 proprotein 6 0.03 0.07 0.02
P78380 OLR1 Oxidized low-density lipoprotein receptor 1 17 0.02 0.0 0.0
Q9GZV9 FGF23 Fibroblast growth factor 23 13 0.02 0.0 0.0
P07711 CTSL Procathepsin L 10 0.02 0.05 0.02
Q6NW40 RGMB RGM domain family member B 16 0.02 0.1 0.02
O15169 AXIN1 Axin-1 15 0.02 0.0 0.0
Q2MKA7 RSPO1 R-spondin-1 12 0.02 0.03 0.05
Q9NSA1 FGF21 Fibroblast growth factor 21 7 0.02 0.05 0.05
P09603 CSF1 Macrophage colony-stimulating factor 1 16 0.02 0.02 0.01
P35318 ADM Pro-adrenomedullin 22 0.02 0.02 0.0
O95998 IL18BP Interleukin-18-binding protein 12 0.02 0.02 0.01
O15197 EPHB6 Ephrin type-B receptor 6 13 0.02 0.08 0.03
Q96GW7 BCAN Brevican core protein 4 0.02 0.03 0.01
Q15109 AGER Advanced glycosylation end product-specific receptor 13 0.02 0.04 0.01
O14625 CXCL11 C-X-C motif chemokine 11 6 0.02 0.01 0.03
P02760 AMBP Protein AMBP 3 0.02 0.04 0.01
P42574 CASP3 Caspase-3 13 0.02 0.0 0.0
Q16651 PRSS8 Prostasin 4 0.02 0.0 0.01
P12644 BMP4 Bone morphogenetic protein 4 6 0.02 0.0 0.02
P54760 EPHB4 Ephrin type-B receptor 4 14 0.02 0.02 0.02
Q92876 KLK6 Kallikrein-6 4 0.02 0.01 0.01
Q16288 NTRK3 NT-3 growth factor receptor 7 0.02 0.04 0.02
P00797 REN Renin 7 0.02 0.01 0.0
P80098 CCL7 C-C motif chemokine 7 4 0.02 0.0 0.04
P41271 NBL1 Neuroblastoma suppressor of tumorigenicity 1 12 0.02 0.01 0.0
Q07011 TNFRSF9 Tumor necrosis factor receptor superfamily member 9 6 0.02 0.06 0.01
P15085 CPA1 Carboxypeptidase A1 6 0.02 0.02 0.01
Q99075 HBEGF Proheparin-binding EGF-like growth factor 5 0.02 0.0 0.01
P13725 OSM Oncostatin-M 7 0.02 0.01 0.01
P02452 COL1A1 Collagen alpha-1 2 0.02 0.0 0.0
P01127 PDGFB Platelet-derived growth factor subunit B 3 0.02 0.06 0.0
O60609 GFRA3 GDNF family receptor alpha-3 7 0.02 0.01 0.02
P04275 VWF von Willebrand factor 7 0.02 0.02 0.06
O94907 DKK1 Dickkopf-related protein 1 13 0.02 0.02 0.0
P29965 CD40LG CD40 ligand 4 0.02 0.0 0.0
P40225 THPO Thrombopoietin 2 0.01 0.01 0.01
P57087 JAM2 Junctional adhesion molecule B 4 0.01 0.0 0.0
Q9BYF1 ACE2 Angiotensin-converting enzyme 2 10 0.01 0.01 0.03
O95750 FGF19 Fibroblast growth factor 19 13 0.01 0.01 0.02
O00626 CCL22 C-C motif chemokine 22 7 0.01 0.01
P14780 MMP9 Matrix metalloproteinase-9 9 0.01 0.0 0.0
Q15389 ANGPT1 Angiopoietin-1 11 0.01 0.01 0.0
P04085 PDGFA Platelet-derived growth factor subunit A 11 0.01 0.01 0.0
P21980 TGM2 Protein-glutamine gamma-glutamyltransferase 2 2 0.01 0.01 0.02
Q9P126 CLEC1B C-type lectin domain family 1 member B 3 0.01 0.0 0.0
P19883 FST Follistatin 4 0.01 0.01 0.01
O14594 NCAN Neurocan core protein 3 0.01 0.01 0.0
Q9HCK4 ROBO2 Roundabout homolog 2 4 0.01 0.01 0.01
P13232 IL7 Interleukin-7 1 0.01 0.0 0.01
P04179 SOD2 Superoxide dismutase 5 0.01 0.02 0.0
Q9NZQ7 CD274 Programmed cell death 1 ligand 1 1 0.01 0.0 0.0
P09919 CSF3 Granulocyte colony-stimulating factor 1 0.01 0.01 0.0
O75509 TNFRSF21 Tumor necrosis factor receptor superfamily member 21 1 0.01 0.0
P23560 BDNF Brain-derived neurotrophic factor 1 0.01 0.0
Q9UJM8 HAO1 Hydroxyacid oxidase 1 1 0.01 0.0 0.0
P05121 SERPINE1 Plasminogen activator inhibitor 1 1 0.01 0.0 0.0
Q08629 SPOCK1 Testican-1 2 0.01 0.03 0.0
P00533 EGFR Epidermal growth factor receptor 1 0.01 0.02
P05112 IL4 Interleukin-4 1 0.01 0.01 0.0
P78556 CCL20 C-C motif chemokine 20 2 0.01 0.0 0.0
O00253 AGRP Agouti-related protein 1 0.01 0.0 0.0
P10145 CXCL8 Interleukin-8 1 0.01 0.0 0.01
Q16620 NTRK2 BDNF/NT-3 growth factors receptor 1 0.01 0.0 0.0
P02144 MB Myoglobin 2 0.01 0.0 0.0
P35225 IL13 Interleukin-13 1 0.01
Q9NRJ3 CCL28 C-C motif chemokine 28 1 0.01 0.0 0.0
P19438 TNFRSF1A Tumor necrosis factor receptor superfamily member 1A 1 0.01 0.0 0.0
Q16698 DECR1 2 4-dienoyl-CoA reductase mitochondrial 1 0.01 0.01
P20333 TNFRSF1B Tumor necrosis factor receptor superfamily member 1B 1 0.01 0.04 0.01
P25116 F2R Proteinase-activated receptor 1 2 0.01 0.02 0.0
Q9UKP3 ITGB1BP2 Integrin beta-1-binding protein 2 1 0.01 0.0 0.0
O95630 STAMBP STAM-binding protein 1 0.01
Q9Y6K9 IKBKG NF-kappa-B essential modulator 1 0.01 0.0 0.0
Q9Y624 F11R Junctional adhesion molecule A 1 0.01 0.0 0.0